NAMkind Liver
NAMkind Intestinal models
NAMkind Liver
VivoSim offers several types of liver testing
- In silico liver toxicology prediction – informed by extensive data from our human microtissue liver testing of a wide set of drugs, VivoSim can screen drug structures in silico to predict liver toxicity not seen using other methods
- Drug candidate screening – complex 3d liver model screening for lead optimization or SAR stages
- Investigative toxicology – bespoke liver toxicology models for your needs
- Mitochondrial tox – innovative approaches to this scientific challenge
- Bile acid tox and Bile Salt Export Pump (BSEP) issues
NAMkind Intestinal models
- Diarrhea in silico prediction (coming soon) – screen compounds against a predictive AI / machine learning model trained on clinical and preclinical including NAM data
- Diarrhea assay – first in field diarrhea-causing potential prediction assay
- Quantitation of epithelial barrier integrity in polarized human intestinal epithelium
- Risk assessment of nausea, abdominal pain, and constipation using complex human co-culture systems
- Risk assessment of nausea, abodominal pain, and constipation using in silico predictive AI